The core active components of Dunamis™ are Glutathione, Choline & Milk Thistle. All ingredients are carefully sourced and expertly formulated and blended to ensure maximum efficacy and bioavailability.
The Glutathione in Dunamis is “Opitac™, researched, formulated and developed by Kohjin Life Sciences (Japan), and is extracted via a patented process from Torula Yeast. The patented formulation further addresses the oral bioavailability for increased absorption.
Dunamis’s Choline is made from natural tartaric acid (extracted from Grapes).
The Choline in Dunamis is made by Belgium’s Azingro NV, produced from natural tartaric acid extracted from grapes and a patented formulation to ensure bioavailability.
Your cells contain glutathione, which is a substance made from three amino acids: cysteine, glutamate, and glycine. Glutathione acts as an important antioxidant in your body. That means it helps combat free radicals. These are molecules that can damage your body’s cells.
Glutathione plays a role in many chemical reactions in your body. It also helps detoxify chemicals, including some that your body creates naturally, as well as pollutants and drugs.
Your supply of glutathione decreases as you get older, possibly because your body can’t create as much. Lower glutathione levels appear to go hand-in-hand with poorer health. For instance, lower levels may play a role in many conditions that are more likely to develop in older people.
Your glutathione levels may also decrease during certain health problems, such as:
Glutathione is a powerful antioxidant that is made in the body’s cells. Its levels decrease as a result of aging, stress, and toxin exposure. Boosting glutathione may provide many health benefits, including reduction of oxidative stress.
The Glutathione in Dunamis is provided by “Opitac™, researched, formulated and developed by Kohjin Life Sciences (Japan), and is extracted via a patented process from Torula Yeast. The patented formulation further addresses the oral bioavailability for increased absorption.
1. Antioxidant activity
Free radicals may contribute to aging and some diseases. Antioxidants help to counteract free radicals and protect the body from their damaging effects. Glutathione is a very strong antioxidant, partly because high concentrations can be found in every cell in the body.
2. Preventing cancer progression
Some research shows that glutathione has a role in preventing the progression of cancer. However, the same research indicates that glutathione may make tumors less sensitive to chemotherapy, which is a common cancer treatment. Determining the effects of glutathione on cancer will require more research.
3. Reducing cell damage in liver disease
Hepatitis, alcohol abuse, and fatty liver disease all damage the cells of the liver. A small 2017 clinical trial concludes that glutathione could help treat non-alcoholic fatty liver disease due to its antioxidant properties and potential to detoxify. The researchers note that larger studies are needed to confirm this effect.
4. Improving insulin sensitivity
Insulin resistance can result in the development of type 2 diabetes. The production of insulin causes the body to move glucose (sugar) from the blood and into cells that use it for energy. A small 2018 study indicates that people with insulin resistance tend to have lower glutathione levels, particularly if they have experienced complications, such as neuropathy or retinopathy. A 2013 study reaches similar conclusions.
5. Reducing symptoms of Parkinson’s disease
According to some research, there is evidence that maintaining glutathione levels may help with the symptoms of Parkinson’s disease. The findings appear to support injected glutathione as a potential therapy, but there is little evidence about oral supplementation. Further research is necessary to support its use.
6. Reducing ulcerative colitis damage
Like other inflammatory diseases, ulcerative colitis has been linked to oxidative damage and stress. A 2003 animal study suggests that glutathione supplementation can improve some of the damage to the colon in rats. Determining the effects of glutathione on ulcerative colitis will require more research in humans.
7. Treating autism spectrum disorders
There is some evidence that children with autism have lower levels of glutathione than neurotypical children, or those without autism. In 2011, researchers found that oral glutathione supplements or injections might reduce some effects of autism. However, the team did not look specifically at the children’s symptoms to see if any had improved, so further research is needed to determine this impact.
Choline is a nutrient that supports various bodily functions, including cellular growth and metabolism. The body makes some choline, but the majority comes from dietary sources. In 1998, the Institute of Medicine officially recognized choline as an essential nutrient. However, some research suggests that most people do not get enough of it.
Choline is an essential nutrient that regulates vital bodily functions, such as forming cell membranes and aiding communication between neurons. The body does not produce enough choline on its own, so people need to get it from food sources, such as meat, eggs, and vegetables.
Current scientific studies suggest that choline may improve memory and cognition and reduce the risk of ischemic stroke.
Choline supports brain development and growth in newborn babies. Research also suggests that choline may reduce the risk of preeclampsia and congenital irregularities.
Though the recommended intake for choline is relatively low (125–550 mg per day), most people do not get enough.
Choline deficiency can cause muscle and liver disease and contribute to cardiovascular disease, dementia, and neural tube irregularities in infants.
1. Cell maintenance:
The body uses choline to produce fats that make up cellular membranes.
2. DNA synthesis:
Choline, along with other nutrients such as folate and vitamin B-12, can affect gene expression.
3. Nervous system functioning:
The body converts choline into a neurotransmitter that affects the nerves and plays a role in regulating automatic bodily functions, such as breathing and heart rate.
4. Improving memory and cognition
Choline is an essential nutrient for brain development. In one observational study of 2,195 participants aged 70–74 years, those with higher choline levels had better cognitive functioning than participants with low choline levels. Another observational study from 2019 found that inadequate levels of choline, vitamin C, and zinc were associated with poorer working memory in older men.
5. Protecting heart health
The authors of a 2018 study found an association between higher dietary intakes of choline and a lower risk of ischemic stroke. The study looked at nearly 4,000 African American participants, with an average 9 year follow-up period.
6. Boosting metabolism
Some research has shown that choline plays a role in metabolizing fats. The authors of a small 2014 study found that female athletes who took choline supplements had lower body mass indexes (BMIs) and leptin levels than the control group. Leptin is a hormone that controls body fat.
7. Reducing the risk of pregnancy complications
Choline can affect fetal development and may influence pregnancy outcomes. In one 2013 study, for example, women in their third trimester of pregnancy received either 480 milligrams (mg) or 930 mg of choline per day. Those who took higher doses had reduced markers of preeclampsia. Symptoms of preeclampsia include high blood pressure, swelling, and severe headaches.
8. Improving cystic fibrosis symptoms
One 2018 study found that choline supplementation improved lung function and reduced symptoms of fatty liver disease in 10 adult males with cystic fibrosis.
Choline deficiency can contribute to the following health conditions:
· cardiovascular disease
· neurological conditions, such as Alzheimer’s disease
· nonalcoholic fatty liver disease
· neural tube irregularities
· muscle damage
Milk thistle (Silybum marianum) is a perennial herb believed to have medicinal properties. The seeds contain silymarin, a group of compounds said to have antioxidant and anti-inflammatory effects. Milk thistle is commonly used as a home remedy to treat liver problems, often under the presumption that it will “detoxify” the liver.
1. Supports liver health
One of the most common uses of milk thistle is to treat liver problems. A 2016 study found that milk thistle improved diet-induced liver damage in mice. More evidence is needed to prove that milk thistle benefits human livers in the same way. However, researchers theorize that it does. The active ingredient in milk thistle, silymarin, acts as an antioxidant by reducing free radical production. Scientists think this creates a detoxifying effect, which is why it is milk thistle may be beneficial for liver problems.
Until more research is carried out, however, milk thistle is not recommended as the primary treatment option for liver problems. But it may be a helpful complementary treatment to try.
2. Promotes skin health
Milk thistle oil may be used topically to improve skin health. Milk thistle may help to promote healthy skin. A 2015 study found that milk thistle helped improve inflammatory skin conditions when applied to the skin of mice.
Milk thistle was also found to have antioxidant and anti-aging effects on human skin cells in a laboratory environment in another study. Further research on humans is needed to identify what benefits a person can expect from applying milk thistle to their skin.
3. Reduces cholesterol
High cholesterol can lead to problems with heart health and increase a person’s chance of stroke. A 2006 study suggests milk thistle may play an important role keeping cholesterol levels down. It found that cholesterol levels were lower in people taking milk thistle to treat diabetes than those taking a placebo.
4. Supports weight loss
Initial animal research conducted in 2016 found that silymarin caused weight loss in mice that were fed a diet intended to cause weight gain.
This suggests milk thistle may be beneficial for those looking to lose weight. More research into the effects of milk thistle on weight loss in humans is needed to confirm this, however.
5. Reduces insulin resistance
A study on mice found milk thistle extract helped to reduce insulin resistance. Insulin resistance is a problem for people with type 2 diabetes.
Although this research suggests milk thistle could play a role in diabetes management, more research is needed to confirm whether milk thistle reduces insulin resistance and supports diabetes management.
6. Improves allergic asthma symptoms
The active ingredient in milk thistle can help to reduce inflammation. A 2012 study found that silymarin helped to protect against inflammation in the airways of mice with allergic asthma. More research is needed to see if silymarin benefits asthma symptoms in humans.
7. Limits the spread of cancer
Milk thistle may help to stop the spread of certain types of cancer. A 2016 review found that milk thistle extract inhibited the growth of cancerous cells in colorectal cancer. More research is needed to determine how milk thistle may be used to help fight cancer.
8. Supports bone health
Milk thistle tea may help to prevent bone loss caused by a lack of estrogen. Milk thistle may play an essential role in supporting bone health. A 2013 study found that milk thistle helped to prevent bone loss. The study looked specifically at bone loss caused by a deficiency in estrogen. It is not yet clear whether milk thistle is equally beneficial for bone loss with a different cause.
Further studies are needed before it is safe to conclude that milk thistle supports bone health in humans.
9. Improves cognition
A 2015 study found that milk thistle increased resistance to oxidative stress. Oxidative stress is a potential cause of Alzheimer’s disease. In this way, milk thistle may help improve cognition and treat degenerative conditions that affect the mind. More research on humans is needed to confirm the effects of milk thistle on cognition.
10. Boosts the immune system
Milk thistle may help strengthen a person’s immune response and help them fight off infection. A 2016 study on an animal model found that milk thistle extract improved the immunity when consumed. An older study found that milk thistle extract had a positive effect on immune response in humans.
Excessive Glutathione may incur the following side effects:
· Abdominal cramps
· Trouble breathing due to bronchial constriction
· Allergic reactions, such as rash
Too much choline may cause the following:
· Fishy body odour
· Heavy sweating and salivation
· Low blood pressure
· Liver damage
Milk thistle may trigger a number of side effects, including:
· Abdominal bloating and gas.
· Less commonly,
· Muscle aches,
· Joint pain,
· Sexual dysfunction
You should avoid taking Dunamis or consult a physician prior to consuming Dunamis, if you are allergic to ragweed, daisies, artichokes, kiwi, or plants in the aster family.