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Choline

Dunamis Clinical Resource

Choline Introduction Choline is an essential nutrient that is naturally present in some foods and available as a dietary supplement. Choline is a source of methyl groups needed for many steps in metabolism. The body needs choline to synthesize phosphatidylcholine and sphingomyelin, two major phospholipids vital for cell membranes. Therefore, all plant and animal cells… Continue reading Choline

Dunamis Clinical Resource

Choline’s role in maintaining liver function: new evidence for epigenetic mechanisms

Dunamis Clinical Resource

Choline’s role in maintaining liver function: new evidence for epigenetic mechanisms Abstract Purpose of review—Humans eating diets low in choline develop fatty liver and liver damage. Rodents fed choline–methionine-deficient diets not only develop fatty liver, but also progress to develop fibrosis and hepatocarcinoma. This review focuses on the role of choline in liver function, with… Continue reading Choline’s role in maintaining liver function: new evidence for epigenetic mechanisms

Dunamis Clinical Resource

Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study

Dunamis Clinical Resource

Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study Abstract Background: Glutathione plays crucial roles in the detoxification and antioxidant systems of cells and has been used to treat acute poisoning and chronic liver diseases by intravenous injection. This is a first study examining the therapeutic effects… Continue reading Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study

Dunamis Clinical Resource

19 Potential Benefits of Glutathione + Side Effects

Dunamis Clinical Resource

19 Potential Benefits of Glutathione + Side Effects What is Glutathione? Why do Some Call it “the Master Antioxidant?” Glutathione (GSH) is your body’s strongest antioxidant. It has an enormous capacity to combat oxidative stress and neutralize harmful free radicals. Chemically speaking, glutathione is a tripeptide made up of 3 amino acids Glutamic acid Cysteine… Continue reading 19 Potential Benefits of Glutathione + Side Effects

Dunamis Clinical Resource

The Importance and Regulation of Hepatic Glutathione

Dunamis Clinical Resource

The Importance and Regulation of Hepatic Glutathione Glutathione plays a key role in the liver in detoxification reactions and in regulating the thiol-disulfide status of the cell. Glutathione synthesis is regulated mainly by the availability of precursor cysteine and the concentration of glutathione itself which feeds back to regulate its own synthesis. Degradation of hepatic… Continue reading The Importance and Regulation of Hepatic Glutathione

Dunamis Clinical Resource

The Effects of Oral L-Arginine and L-Citrulline Supplementation on Blood Pressure.

AF-8 Clinical Resource

The Effects of Oral L-Arginine and L-Citrulline Supplementation on Blood Pressure Abstract: Nitric oxide (NO) is a well-known vasodilator produced by the vascular endothelium via the enzyme endothelial nitric oxide synthase (eNOS). The inadequate production of NO has been linked to elevated blood pressure (BP) in both human and animal studies, and might be due… Continue reading The Effects of Oral L-Arginine and L-Citrulline Supplementation on Blood Pressure.

AF-8 Clinical Resource

The metabolic basis of arginine nutrition and pharmacotherapy.

AF-8 Clinical Resource

The metabolic basis of arginine nutrition and pharmacotherapy As an essential precursor for the synthesis of proteins and other molecules with enormous biological importance (including nitric oxide, urea, ornithine, proline, polyamines, glutamate, creatine, agmatine, and dimethylarginines), arginine displays remarkable metabolic and regulatory versatility. > Read More

Kidney Disease (Nephropathy).

AF-8 Clinical Resource

Kidney Disease(Nephropathy) Kidneys are remarkable organs. Inside them are millions oftiny blood vessels that act as filters. Their job is to removewaste products from the blood. Sometimes this filtering system breaks down. Diabetes candamage the kidneys and cause them to fail.Failing kidneys lose their ability to filter out waste products, resulting in kidney disease. >… Continue reading Kidney Disease (Nephropathy).

AF-8 Clinical Resource

Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance

AF-8 Clinical Resource

Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance J Appl Physiol 109: 1394–1403, 2010. First published August 19, 2010; doi:10.1152/japplphysiol.00503.2010.—It has recently been reported that dietary nitrate (NO3) supplementation, which increases plasma nitrite (NO2) concentration, a biomarker of nitric oxide (NO) availability, improves exercise efficiency and exercise tolerance… Continue reading Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance

AF-8 Clinical Resource

Effects of Arginine Supplementation on Athletic Performance Based on Energy Metabolism: A Systematic Review and Meta-Analysis

AF-8 Clinical Resource

Effects of Arginine Supplementation on Athletic Performance Based on Energy Metabolism: A Systematic Review and Meta-Analysis Abstract: Nitric oxide related ergogenic aids such as arginine (Arg) have shown to impact positively on sport performance through several physiological and metabolic mechanisms. However, research results have shown to be controversial. The great differences regarding required metabolic pathways… Continue reading Effects of Arginine Supplementation on Athletic Performance Based on Energy Metabolism: A Systematic Review and Meta-Analysis

AF-8 Clinical Resource

Role of L-Arginine in Nitric Oxide production in health and hypertension.

AF-8 Clinical Resource

1. L-Arginine is the substrate for vascular nitric oxide (NO) formation. Under normal physiological conditions, intracellular L-arginine levels far exceed the Km of NO synthase for Larginine. However, endogenous NO formation is dependent on extracellular L-arginine concentrations, giving rise to the concept of the ‘L-arginine paradox’. 2. Nitric oxide production in epithelial and endothelial cells… Continue reading Role of L-Arginine in Nitric Oxide production in health and hypertension.

AF-8 Clinical Resource

An Antiviral Mechanism of Nitric Oxide: Inhibition of a Viral Protease Does Nitric Oxide Play a Critical Role in Viral Infections?

AF-8 Clinical Resource

An Antiviral Mechanism of Nitric Oxide: Inhibition of a Viral Protease Download Does Nitric Oxide Play a Critical Role in Viral Infections? Download

10 ways to control hypertension without medication

AF-8 Clinical Resource

10 ways to control high blood pressure without medication By making these 10 lifestyle changes, you can lower your blood pressure and reduce your risk of heart disease. By Mayo Clinic Staff If you’ve been diagnosed with high blood pressure, you might be worried about taking medication to bring your numbers down. Lifestyle plays an… Continue reading 10 ways to control hypertension without medication

AF-8 Clinical Resource

Hypertension summed-up

AF-8 Clinical Resource

“What is hypertension or high blood pressure and what causes it?” About high blood pressure, (hypertension) Blood pressure is the measure of the force of blood pushing against blood vessel walls. The heart pumps blood into blood vessels, which carry the blood throughout the body. High blood pressure, also called hypertension, is dangerous because it… Continue reading Hypertension summed-up

AF-8 Clinical Resource

Prevention of diabetes

AF-8 Clinical Resource

Diabetes can cause serious health problems, such as heart disease, stroke, and eye and foot problems. Prediabetes also can cause health problems. The good news is that type 2 diabetes can be delayed or even prevented. The longer you have diabetes, the more likely you are to develop health problems.

What are the symptoms of diabetes?

AF-8 Clinical Resource

What are the symptoms of diabetes? Symptoms of diabetes include increased thirst and urination increased hunger fatigue blurred vision numbness or tingling in the feet or hands sores that do not heal unexplained weight loss Symptoms of type 1 diabetes can start quickly, in a matter of weeks. Symptoms of type 2 diabetes often develop… Continue reading What are the symptoms of diabetes?

AF-8 Clinical Resource

Risk Factors for Type 2 Diabetes

AF-8 Clinical Resource

Your chances of developing type 2 diabetes depend on a combination of risk factors such as your genes and lifestyle. Although you can’t change risk factors such as family history, age, or ethnicity, you can change lifestyle risk factors around eating, physical activity, and weight. These lifestyle changes can affect your chances of developing type 2 diabetes.

Read about risk factors for type 2 diabetes below and see which ones apply to you. Taking action on the factors you can change can help you delay or prevent type 2 diabetes.
You are more likely to develop type 2 diabetes if you

Effects of a Yeast Extract with a High Glutathione Content on Breath Alcohol and Hepatic Function in Human Volunteers

Dunamis Clinical Resource

Effects of a Yeast Extract with a High Glutathione Content on Breath Alcohol and Hepatic Function in Human Volunteers > download

Withania Somnifera & Rheumatoid Arthritis

Jointplex Pro Clinical Resource

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry In vivo, Extract from Withania somnifera Root Ameliorates Arthritis via Regulation of Key Immune Mediators of Inflammation in Experimental Model of Arthritis Abstract BackgroundRheumatoid Arthritis (RA) is a devastating disease characterized by continual addition of leukocytes and T cells within the articular cavity causing inflammation and cartilage destruction.… Continue reading Withania Somnifera & Rheumatoid Arthritis

Jointplex Pro Clinical Resource

Vascular dementia is the second most common cause of dementia and is increasing in prevalence in developing countries.

AF-8 Clinical Resource

Vascular dementia usually occurs in association with vascular risk factors or after transient ischaemic attack (TIA) or stroke and commonly manifests with a decline in cognitive function, apathy and depression, and can eventually result in death.

The blood clot that triggers a thrombotic stroke usually forms inside an artery that already has been narrowed by atherosclerosis.

AF-8 Clinical Resource

This is a condition in which fatty deposits (plaques) build up inside blood vessels.

Alternative Therapeutic Approach for Cartilage Repair.

Jointplex Pro Clinical Resource

Alternative Therapeutic Approach for Cartilage Repair. > download

What is Torula Yeast?

Dunamis Clinical Resource

What Is Torula Yeast? Torula yeast is a type of yeast, one of about 1,500 types of tiny, single-celled fungi. Edible torula yeast grows on wood alcohols. When deactivated and dried, it looks like a tan powder and can be packaged and sold in health and nutrition stores. It adds a smoky, umami flavor to… Continue reading What is Torula Yeast?

Dunamis Clinical Resource

What is inflammation, its associated diseases, symptoms, and causes?

Jointplex Pro Clinical Resource

What is inflammation, its associated diseases, symptoms, and causes? Inflammation is a process by which the body’s white blood cells and substances they produce protect us from infection with foreign organisms, such as bacteria and viruses. However, in some diseases, like arthritis, the body’s defense system — the immune system — triggers an inflammatory response… Continue reading What is inflammation, its associated diseases, symptoms, and causes?

Jointplex Pro Clinical Resource

Understanding Cartilage, Joints and the Aging Process.

Jointplex Pro Clinical Resource

Jointplex Pro contains Curcumin, Boswellia, Withania and ginger, carefully formulated to repair, restore and protect joints and cartilage. More Information Understanding Cartilage, Joints, and the Aging Process. What is osteoarthritis? A lifetime of walking, exercising, and moving can take a toll on your cartilage — the smooth, rubbery connective tissue covering the ends of bones.… Continue reading Understanding Cartilage, Joints and the Aging Process.

Jointplex Pro Clinical Resource

In Vitro and ex Vivo Uptake of Glutathione (GSH) across the Intestinal Epithelium and Fate of Oral GSH after in Vivo Supplementation

Dunamis Clinical Resource

In Vitro and ex Vivo Uptake of Glutathione (GSH) across the Intestinal Epithelium and Fate of Oral GSH after in Vivo Supplementation > download

What causes osteoarthritis and what are the risk factors?

Jointplex Pro Clinical Resource

What are the causes of osteoarthritis? Arthritis involves chronic inflammation of one or more joints in the body. Osteoarthritis (OA) is the most common type of arthritis. In people with OA, the cartilage in one or more joints deteriorates with time. Cartilage is a tough, rubbery substance. Normally, it protects the ends of bones and… Continue reading What causes osteoarthritis and what are the risk factors?

Jointplex Pro Clinical Resource

Impact of Supplementation of KOHJIN Glutathione on Blood Glutathione Level

Dunamis Clinical Resource

Impact of Supplementation of KOHJIN Glutathione on Blood Glutathione Level > download

Thrombosis is the formation of a blood clot, known as a thrombus, within a blood vessel.

AF-8 Clinical Resource

It prevents blood from flowing normally through the circulatory system. Nitric Oxide is essential for the prevention of thrombosis.

Watch for these signs and symptoms if you think you or someone else may be having a stroke.

AF-8 Clinical Resource

Pay attention to when the signs and symptoms begin. The length of time they have been present can affect your treatment options.