Category: AF-8 Clinical Resource

The Effects of Oral L-Arginine and L-Citrulline Supplementation on Blood Pressure Abstract: Nitric oxide (NO) is a well-known vasodilator produced by the vascular endothelium via the enzyme endothelial nitric oxide synthase (eNOS). The inadequate production of NO has been linked to elevated blood pressure (BP) in both human and animal studies, and might be due… Continue reading The Effects of Oral L-Arginine and L-Citrulline Supplementation on Blood Pressure.

The metabolic basis of arginine nutrition and pharmacotherapy As an essential precursor for the synthesis of proteins and other molecules with enormous biological importance (including nitric oxide, urea, ornithine, proline, polyamines, glutamate, creatine, agmatine, and dimethylarginines), arginine displays remarkable metabolic and regulatory versatility. > Read More

Kidney Disease(Nephropathy) Kidneys are remarkable organs. Inside them are millions oftiny blood vessels that act as filters. Their job is to removewaste products from the blood. Sometimes this filtering system breaks down. Diabetes candamage the kidneys and cause them to fail.Failing kidneys lose their ability to filter out waste products, resulting in kidney disease. >… Continue reading Kidney Disease (Nephropathy).

Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance J Appl Physiol 109: 1394–1403, 2010. First published August 19, 2010; doi:10.1152/japplphysiol.00503.2010.—It has recently been reported that dietary nitrate (NO3) supplementation, which increases plasma nitrite (NO2) concentration, a biomarker of nitric oxide (NO) availability, improves exercise efficiency and exercise tolerance… Continue reading Acute L-arginine supplementation reduces the O2 cost of moderate-intensity exercise and enhances high-intensity exercise tolerance

Effects of Arginine Supplementation on Athletic Performance Based on Energy Metabolism: A Systematic Review and Meta-Analysis Abstract: Nitric oxide related ergogenic aids such as arginine (Arg) have shown to impact positively on sport performance through several physiological and metabolic mechanisms. However, research results have shown to be controversial. The great differences regarding required metabolic pathways… Continue reading Effects of Arginine Supplementation on Athletic Performance Based on Energy Metabolism: A Systematic Review and Meta-Analysis

1. L-Arginine is the substrate for vascular nitric oxide (NO) formation. Under normal physiological conditions, intracellular L-arginine levels far exceed the Km of NO synthase for Larginine. However, endogenous NO formation is dependent on extracellular L-arginine concentrations, giving rise to the concept of the ‘L-arginine paradox’. 2. Nitric oxide production in epithelial and endothelial cells… Continue reading Role of L-Arginine in Nitric Oxide production in health and hypertension.

An Antiviral Mechanism of Nitric Oxide: Inhibition of a Viral Protease Download Does Nitric Oxide Play a Critical Role in Viral Infections? Download

10 ways to control high blood pressure without medication By making these 10 lifestyle changes, you can lower your blood pressure and reduce your risk of heart disease. By Mayo Clinic Staff If you’ve been diagnosed with high blood pressure, you might be worried about taking medication to bring your numbers down. Lifestyle plays an… Continue reading 10 ways to control hypertension without medication

“What is hypertension or high blood pressure and what causes it?” About high blood pressure, (hypertension) Blood pressure is the measure of the force of blood pushing against blood vessel walls. The heart pumps blood into blood vessels, which carry the blood throughout the body. High blood pressure, also called hypertension, is dangerous because it… Continue reading Hypertension summed-up

Diabetes can cause serious health problems, such as heart disease, stroke, and eye and foot problems. Prediabetes also can cause health problems. The good news is that type 2 diabetes can be delayed or even prevented. The longer you have diabetes, the more likely you are to develop health problems.